Basilea Pharmaceutica is focused on treating infectious diseases; its marketed products are Cresemba (antifungal) and Zevtera (anti-MRSA antibiotic). In late 2023, it expanded its pipeline to include fosmanogepix, BAL2062 and tonabacase. In January 2024, it acquired the preclinical LptA inhibitor antibiotics programme from Spexis.
There is an ever-increasing need for therapeutic agents that are efficacious against drug-resistant strains of bacteria (eg MRSA) or fungi. Hence the opportunities for Cresemba, Zevtera and fosmanogepix could be significant.
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Adesh Kaul
CFO
David Veitch
CEO
Forecast net debt (CHFm)
N/A
Forecast gearing ratio (%)
N/A
% | 1M | 3M | 12M |
---|---|---|---|
Actual | (11.5) | (9.2) | 12.1 |
Relative | (5.5) | (3.5) | 4.3 |
52 week high/low | CHF47.1/CHF32.2 |
Basilea’s commercial portfolio comprises Cresemba (an antifungal) and Zevtera (an antibiotic). Cresemba is marketed in more than 70 countries. Zevtera is marketed in selected countries in Europe, Latin America, the Middle East, North Africa and Canada. In April 2024, the FDA approved Zevtera for the US, the most lucrative market for the antibiotic; details on the US commercial partner are expected in 2024. Basilea has also re-stocked its clinical and preclinical pipeline. Notably, fosmanogepix is a broad-spectrum antifungal therapy, for which the first of two Phase III trials launched in September 2024. The company reported strong H124 results, with revenues of CHF76.3m and H2-weighed milestone payments (including US$25m from Pfizer in September). Following the recent BARDA agreement (up to US$268m across the 12-year agreement), management upgraded guidance for FY24 (group revenues of CHF203m vs CHF196m previously).
Y/E Dec | Revenue (CHFm) | EBITDA (CHFm) | PBT (CHFm) | EPS (CHFc) | P/E (x) | P/CF (x) |
---|---|---|---|---|---|---|
2022A | 147.8 | 19.6 | 12.3 | 104.10 | 39.0 | N/A |
2023A | 157.6 | 20.8 | 10.8 | 89.66 | 45.2 | N/A |
2024E | 203.0 | 44.1 | 38.9 | 499.44 | 8.1 | N/A |
2025E | 219.1 | 55.5 | 50.7 | 419.42 | 9.7 | N/A |