Standard Life Private Equity Trust — Increasing its investment level

Patria Private Equity Trust (LSE: PPET)

Last close As at 21/12/2024

GBP5.50

10.00 (1.85%)

Market capitalisation

GBP836m

More on this equity

Research: Investment Companies

Standard Life Private Equity Trust — Increasing its investment level

Standard Life Private Equity Trust (SLPET) recorded a NAV total return of 11.7% in the quarter ended 30 June 2021 (last date of portfolio valuations). SLPET benefited from improving public market multiples, driving unrealised portfolio gains to £72.2m (representing c 8.2% return), as well as strong realisations. The average uplift on exits in the quarter reached 29.3%, translating into an average multiple on invested capital of 3.2x. Based on the last reported NAV estimate as at end-October 2021, reflecting end-June 2021 portfolio valuations adjusted for subsequent FX movements and dividend payments, SLPET reported a one-year NAV TR of 36.7%, above the 35.4% return posted by the FTSE All-Share index and 25.6% by the LPX Europe NAV index, used as a broad PE market reference.

Milosz Papst

Written by

Milosz Papst

Head of Content, Investment Trusts

Investment Companies

Standard Life Private Equity Trust

Increasing its investment level

Investment trusts
Private equity funds

3 December 2021

Price

520.0p

Market cap

£800m

AUM

£969m

NAV*

613.0p

Discount to NAV

15.2%

*Including income. As at 31 October 2021.

Yield

2.6%

Ordinary shares in issue

153.7m

Code/ISIN

SLPE/GB0030474687

Primary exchange

LSE

AIC sector

Private equity

52-week high/low

531.9p

345.0p

NAV* high/low

627.1p

479.8p

*Including income.

Gross gearing*

0.0%

Net cash*

4.0%

*As at 31 October 2021.

Fund objective

Standard Life Private Equity Trust’s (SLPET) investment objective is to achieve long-term total returns through holding a diversified portfolio of private equity funds and direct investments into private companies alongside private equity managers (‘co-investments’), a majority of which will have a European focus.

Bull points

Focus on top-performing European private equity managers.

Experienced investment team with strong private equity manager relationships.

Increasing share of direct co-investments should reduce costs on a look-through basis.

Bear points

Ample dry powder in the market translating into high competition for quality assets.

High valuations in most resilient sectors.

Changes to sector exposure take more time due to SLPET’s fund-of-fund structure.

Analyst

Milosz Papst

+44 (0)20 3681 2519

Standard Life Private Equity Trust is a research client of Edison Investment Research Limited

Standard Life Private Equity Trust (SLPET) recorded a NAV total return of 11.7% in the quarter ended 30 June 2021 (last date of portfolio valuations). SLPET benefited from improving public market multiples, driving unrealised portfolio gains to £72.2m (representing c 8.2% return), as well as strong realisations. The average uplift on exits in the quarter reached 29.3%, translating into an average multiple on invested capital of 3.2x. Based on the last reported NAV estimate as at end-October 2021, reflecting end-June 2021 portfolio valuations adjusted for subsequent FX movements and dividend payments, SLPET reported a one-year NAV TR of 36.7%, above the 35.4% return posted by the FTSE All-Share index and 25.6% by the LPX Europe NAV index, used as a broad PE market reference.

Overcommitment ratio returns to 30–75% target range

Source: Standard Life Private Equity Trust, Edison Investment Research

Why invest in SLPET now?

The significant pick-up in M&A and IPO activity, which started in H220, has driven strong and profitable realisation activity in SLPET’s general partners (GPs) and cash distributions to SLPET. Consequently, the best-performing GPs continue to deliver attractive long-term returns and SLPET benefits from its selection of high-conviction GPs with which it has longstanding relationships. Moreover, it has a well-balanced portfolio in terms of cyclical and non-cyclical sectors, with combined tech and healthcare exposure at end-June 2021 of 39%.

The analyst’s view

SLPET’s investment activity has picked up in the recent months, with a notable volume of co-investments of £53m in the second half of the financial year 2021 (ended 30 September 2021), or c 25% of new commitments/investments in the period. As a result, its overcommitment ratio reached 33% at end-October 2021 (versus 25% and 28% at end-March 2021 and end-June 2021, respectively), which is already in line with management target of 30–75% (although closer to the lower bound). At end-October 2021, SLPET held liquid resources amounting to £37.6m. Together with the fully undrawn £200m syndicated credit facility, it represents a robust coverage ratio of outstanding commitments of 44%. On 29 October 2021, SLPET made its third interim dividend payment for FY21, amounting to 3.4p per share, which constitutes an annualised yield of 2.6%, assuming a dividend for the year of 13.6p.

Strong equity markets support valuation multiples

As at end-October 2021, the estimated NAVPS amounted to 613.0p, which translates into a one-year total return of 36.7%, compared to 35.4% recorded by the FTSE All-Share Index (official benchmark) and 25.6% posted by the LPX Europe NAV index, which we use as a broad PE market reference. However, we note that all SLPET’s portfolio holdings were last valued at 30 June 2021 (except for new investments completed after that date) and its NAV has been adjusted for subsequent FX movements and dividend payments.

Exhibit 1: Price, NAV and index TR performance, one-year rebased, to end-October 2021

Exhibit 2: Price, NAV and benchmark TR performance (%), to end-October 2021

Source: Refinitiv, Edison Investment Research. Note: SLPET NAV data stream consists of actual figures for quarter-ends and NAV estimates for the remaining months.

Source: Refinitiv, Edison Investment Research. Note: Three-, five- and 10-year performance figures annualised.

Exhibit 1: Price, NAV and index TR performance, one-year rebased, to end-October 2021

Source: Refinitiv, Edison Investment Research. Note: SLPET NAV data stream consists of actual figures for quarter-ends and NAV estimates for the remaining months.

Exhibit 2: Price, NAV and benchmark TR performance (%), to end-October 2021

Source: Refinitiv, Edison Investment Research. Note: Three-, five- and 10-year performance figures annualised.

The last reported actual NAV (dated 30 June 2021) of 630.6p implies a 36.9% one-year total return and 11.7% TR in Q3FY21 (SLPET’s financial year ended on 30 September 2021). The robust three-month performance was primarily driven by an increase in the valuation of existing underlying holdings, representing a c 8.2% return, including positive foreign exchange effects, contributing 0.6% to the improvement. It was further assisted by healthy revaluations of exited underlying investments, with the £45.4m distributions received in Q321 resulting in a £31.3m net realised gain, or 3.2x acquisition cost multiple. We also note that the average valuation uplift on exit in the quarter reached 29.3%.

Exhibit 3: NAV per share development in Q321 and to end-October 2021

Source: Standard Life Private Equity Trust, Edison Investment Research

Strong NAV expansion, coupled with favourable public market dynamics, resulted in SLPET’s impressive one-year share price total return of 61.1% as at end-October 2021. As the share price rally continued in November, the current discount to NAV amounts to 15.2%, which is narrower than the one-year and three-year averages of 19.9% and 21.7%, respectively.

Recent returns broadly in line with other PE funds-of-funds

We continue to compare SLPET’s performance with a peer group including PE funds-of-funds, putting more emphasis on mid- to long-term performance, which not only better aligns with a PE investment horizon, but also limits the impact of different asset valuation dates and, consequently, FX changes. We note that the entire SLPET portfolio and the majority of its peers’ holdings were revalued as at end-June 2021 and adjusted for subsequent FX movements. Based on the last reported figures, SLPET’s three-year NAV TR of 62% ranks it in the middle of the peer group, although sitting below the group average of 70.9%. Its five-year NAV return is at the lower end of the peer range, but still represents a very robust return of c 100%, significantly ahead of the LPX Europe NAV Index over the period (79.2% NAV TR in sterling terms), which we consider a good indicator of the broad European PE market. The company has also outperformed the index in the ten-year period, posting a total return of 236.4% (vs 180.2%), which ranks fourth within the peer group, sitting slightly below the average return of 249.4%.

We note that SLPET’s exposure to co-investments (11%) is currently below peer average of 28%, according to our calculations. As these are not subject to a two-layer fee structure, further growth of SLPET’s co-investments portfolio could further enhance the company’s performance.

SLPET’s shares are trading at a 15.2% discount to NAVPS, which is narrower than the peer group average of 18.4%, with limited deviations among the group. The company’s dividend yield reached 2.6%, which is slightly below the average of the other two dividend paying peers of 2.8% (the average of the whole group is 1.4%).

Exhibit 4: Selected peer group as at 19 November 2021*

% unless stated otherwise

Market cap £m

NAV TR
1 year

NAV TR
3 year

NAV TR
5 year

NAV TR
10 year

Ongoing
charge

Perf.
fee

Discount
(cum-fair)

Net
gearing

Dividend
yield

Standard Life Private Equity Trust

799.5

36.7

62.0

100.4

236.4

1.14

No

(15.2)

96

2.6

BMO Private Equity Trust

344.2

57.1

79.0

119.3

247.0

1.30

Yes

(20.8)

112

3.7

HarbourVest Global Private Equity

2,164.3

54.5

96.2

152.6

295.0

1.29

Yes**

(16.1)

100

0.0

ICG Enterprise Trust

856.5

37.5

57.2

111.3

213.3

1.50

Yes

(17.9)

100

1.9

Pantheon International

1,732.9

31.0

51.3

89.2

242.5

1.22

Yes

(18.6)

100

0.0

Peer average

1,274.5

45.0

70.9

118.1

249.4

1.33

-

(18.4)

103.2

1.4

Rank in peer group

4

4

3

4

4

5

-

1

3

2

Source: Morningstar, Edison Investment Research. Note: TR = total return. Net gearing is total assets less cash and equivalents as a percentage of net assets (100 = ungeared). *12-month performance based on latest available ex-par NAV: SLPET, Pantheon and HarbourVest – end-October; BMO Private Equity Trust – endSeptember; ICG Enterprise Trust – end-July. **No performance fee is charged at the HVPE level, but it is charged on the HarbourVest secondary and direct funds.

Investment activity pick-up in H221

SLPET’s investment activity has accelerated recently, as new commitments in H221 amounted to c £211m, according to our calculations, which represents a more than twofold increase on the H121 total of £88.4m. This consists of £112m primary investments, £46m secondaries and £53m co-investments. This brought SLPET’s outstanding commitments as at end-FY21 to £559.5m, which slightly decreased in October 2021 to £544.7m (of which £42.2m commitments were considered by the investment manager as unlikely to be drawn), as the company completed new investments amounting to another £24m in that month.

Primary investments focused on technology and healthcare

In June 2021, SLPET made two US$35m primary commitments to Permira Growth Opportunities II and Excellere Capital Fund IV, with the former targeting smaller, technology growth companies, while the latter focuses on founder-led, lower mid-market companies in North America from business services, healthcare and industrial sectors. In the same month, the company announced a €30m primary investment in Nordic Capital Evolution Fund I, which operates mainly in northern Europe, selecting non-cyclical growth opportunities within the healthcare, technology & payments and financial services sectors.

In July 2021, SLPET committed US$31.5m to Advent Global Technology II fund, focused on smaller technological companies and co-investments in larger deals alongside other Advent-managed funds. We note that the targeted fund volume amounts to US$3bn just two years after the first Advent Global Technology fund collected US$2bn, which confirms the strong market sentiment towards IT businesses. The healthcare sector targeted by Archimed MED III fund, to which SLPET made a €15m commitment in July, continues to attract investor interest. We note that the fund was well oversubscribed, as it closed the fund-raising process within two months at €650m hard cap (versus the original target of €500m).

In October 2021, the first month of SLPET’s FY22, the company committed another €20m to Capiton VI fund, participating in a final close of a fund launched in 2020. It has already invested in CEDES, a sensor producer, MiP Pharma Group, an international manufacturer and distributor of generic pharmaceuticals with particular emphasis on anti-infectives, and Wundex, a German medical and physiotherapy company.

Selected secondary investments

In H221, SLPET was also active in the secondaries market, as it sold interests in Equistone Partners Europe Fund III and Terra Firma Capital Partners III in June for a combined total of €1.3m. It was followed by a US$62.5m investment in Structured Solutions IV Primary Holdings with initial funding of US$38.4m paid at the end of the month. The transaction’s goal was to provide necessary diversification through the acquisition of a stake in a balanced portfolio of recent vintage large-cap buyout funds in Europe and North America. Finally, in October 2021, SLPET sold its interest in Equistone Partners Europe Fund VI for €18.2m while there was still €14.2m in outstanding commitments prior to the date of sale.

Building co-investment volume

In H221, SLPET conducted a number of co-investments amounting to c £53m, which constitutes c 25% of all new commitments/investments (including secondaries) made in the period. This brings it closer to reaching the mid-term target of a c 20% share of co-investments in portfolio NAV. We estimate that the end-FY21 exposure could have reached 11%, which is slightly above management’s expectation of 8–10%. Having said that, we note that our estimate is based on the end-June 2021 valuation of portfolio holdings.

In June 2021, SLPET made a €4.9m co-investment in KD Pharma, the largest Omega-3 pharma producer worldwide, with 11 offices in eight countries and a portfolio consisting of more than 1,000 pharmaceutical and nutrition products. In July, SLPET completed three co-investments worth €10m each. These include Wundex (see above) and Questel, a software publisher and service provider for intellectual property, trademark law and innovation sectors as well as an undisclosed consumer health business. The following month, SLPET made a €10.5m commitment to Eurazeo Payment Luxembourg Fund SCSp, a single asset vehicle holding an investment in the global integrated payment provider Planet. It was followed by a US$10m coinvestment in Insightsoftware, a leading ‘office of the CFO’ software provider. Finally, in September 2021, SLPET made a €7.9m co-investment in Riskalyze, a US provider of risk tolerance software for financial advisors.

We note that the company has continued momentum into FY22, starting the financial year with a £4.2m co-investment in SportPursuit, a flash sale e-commerce business selling clearance stock from leading sports and outdoor brands, and €7.5m in SuanFarma, a manufacturer, CDMO and distributor of active pharmaceutical and nutraceutical ingredients, in October 2021.

General disclaimer and copyright

This report has been commissioned by Standard Life Private Equity Trust and prepared and issued by Edison, in consideration of a fee payable by Standard Life Private Equity Trust. Edison Investment Research standard fees are £60,000 pa for the production and broad dissemination of a detailed note (Outlook) following by regular (typically quarterly) update notes. Fees are paid upfront in cash without recourse. Edison may seek additional fees for the provision of roadshows and related IR services for the client but does not get remunerated for any investment banking services. We never take payment in stock, options or warrants for any of our services.

Accuracy of content: All information used in the publication of this report has been compiled from publicly available sources that are believed to be reliable, however we do not guarantee the accuracy or completeness of this report and have not sought for this information to be independently verified. Opinions contained in this report represent those of the research department of Edison at the time of publication. Forward-looking information or statements in this report contain information that is based on assumptions, forecasts of future results, estimates of amounts not yet determinable, and therefore involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of their subject matter to be materially different from current expectations.

Exclusion of Liability: To the fullest extent allowed by law, Edison shall not be liable for any direct, indirect or consequential losses, loss of profits, damages, costs or expenses incurred or suffered by you arising out or in connection with the access to, use of or reliance on any information contained on this note.

No personalised advice: The information that we provide should not be construed in any manner whatsoever as, personalised advice. Also, the information provided by us should not be construed by any subscriber or prospective subscriber as Edison’s solicitation to effect, or attempt to effect, any transaction in a security. The securities described in the report may not be eligible for sale in all jurisdictions or to certain categories of investors.

Investment in securities mentioned: Edison has a restrictive policy relating to personal dealing and conflicts of interest. Edison Group does not conduct any investment business and, accordingly, does not itself hold any positions in the securities mentioned in this report. However, the respective directors, officers, employees and contractors of Edison may have a position in any or related securities mentioned in this report, subject to Edison's policies on personal dealing and conflicts of interest.

Copyright: Copyright 2021 Edison Investment Research Limited (Edison).

Australia

Edison Investment Research Pty Ltd (Edison AU) is the Australian subsidiary of Edison. Edison AU is a Corporate Authorised Representative (1252501) of Crown Wealth Group Pty Ltd who holds an Australian Financial Services Licence (Number: 494274). This research is issued in Australia by Edison AU and any access to it, is intended only for "wholesale clients" within the meaning of the Corporations Act 2001 of Australia. Any advice given by Edison AU is general advice only and does not take into account your personal circumstances, needs or objectives. You should, before acting on this advice, consider the appropriateness of the advice, having regard to your objectives, financial situation and needs. If our advice relates to the acquisition, or possible acquisition, of a particular financial product you should read any relevant Product Disclosure Statement or like instrument.

New Zealand

The research in this document is intended for New Zealand resident professional financial advisers or brokers (for use in their roles as financial advisers or brokers) and habitual investors who are “wholesale clients” for the purpose of the Financial Advisers Act 2008 (FAA) (as described in sections 5(c) (1)(a), (b) and (c) of the FAA). This is not a solicitation or inducement to buy, sell, subscribe, or underwrite any securities mentioned or in the topic of this document. For the purpose of the FAA, the content of this report is of a general nature, is intended as a source of general information only and is not intended to constitute a recommendation or opinion in relation to acquiring or disposing (including refraining from acquiring or disposing) of securities. The distribution of this document is not a “personalised service” and, to the extent that it contains any financial advice, is intended only as a “class service” provided by Edison within the meaning of the FAA (i.e. without taking into account the particular financial situation or goals of any person). As such, it should not be relied upon in making an investment decision.

United Kingdom

This document is prepared and provided by Edison for information purposes only and should not be construed as an offer or solicitation for investment in any securities mentioned or in the topic of this document. A marketing communication under FCA Rules, this document has not been prepared in accordance with the legal requirements designed to promote the independence of investment research and is not subject to any prohibition on dealing ahead of the dissemination of investment research.

This Communication is being distributed in the United Kingdom and is directed only at (i) persons having professional experience in matters relating to investments, i.e. investment professionals within the meaning of Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005, as amended (the "FPO") (ii) high net-worth companies, unincorporated associations or other bodies within the meaning of Article 49 of the FPO and (iii) persons to whom it is otherwise lawful to distribute it. The investment or investment activity to which this document relates is available only to such persons. It is not intended that this document be distributed or passed on, directly or indirectly, to any other class of persons and in any event and under no circumstances should persons of any other description rely on or act upon the contents of this document.

This Communication is being supplied to you solely for your information and may not be reproduced by, further distributed to or published in whole or in part by, any other person.

United States

Edison relies upon the "publishers' exclusion" from the definition of investment adviser under Section 202(a)(11) of the Investment Advisers Act of 1940 and corresponding state securities laws. This report is a bona fide publication of general and regular circulation offering impersonal investment-related advice, not tailored to a specific investment portfolio or the needs of current and/or prospective subscribers. As such, Edison does not offer or provide personal advice and the research provided is for informational purposes only. No mention of a particular security in this report constitutes a recommendation to buy, sell or hold that or any security, or that any particular security, portfolio of securities, transaction or investment strategy is suitable for any specific person.

Frankfurt +49 (0)69 78 8076 960

Schumannstrasse 34b

60325 Frankfurt

Germany

London +44 (0)20 3077 5700

280 High Holborn

London, WC1V 7EE

United Kingdom

New York +1 646 653 7026

1185 Avenue of the Americas

3rd Floor, New York, NY 10036

United States of America

Sydney +61 (0)2 8249 8342

Level 4, Office 1205

95 Pitt Street, Sydney

NSW 2000, Australia

Frankfurt +49 (0)69 78 8076 960

Schumannstrasse 34b

60325 Frankfurt

Germany

London +44 (0)20 3077 5700

280 High Holborn

London, WC1V 7EE

United Kingdom

New York +1 646 653 7026

1185 Avenue of the Americas

3rd Floor, New York, NY 10036

United States of America

Sydney +61 (0)2 8249 8342

Level 4, Office 1205

95 Pitt Street, Sydney

NSW 2000, Australia

General disclaimer and copyright

This report has been commissioned by Standard Life Private Equity Trust and prepared and issued by Edison, in consideration of a fee payable by Standard Life Private Equity Trust. Edison Investment Research standard fees are £60,000 pa for the production and broad dissemination of a detailed note (Outlook) following by regular (typically quarterly) update notes. Fees are paid upfront in cash without recourse. Edison may seek additional fees for the provision of roadshows and related IR services for the client but does not get remunerated for any investment banking services. We never take payment in stock, options or warrants for any of our services.

Accuracy of content: All information used in the publication of this report has been compiled from publicly available sources that are believed to be reliable, however we do not guarantee the accuracy or completeness of this report and have not sought for this information to be independently verified. Opinions contained in this report represent those of the research department of Edison at the time of publication. Forward-looking information or statements in this report contain information that is based on assumptions, forecasts of future results, estimates of amounts not yet determinable, and therefore involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of their subject matter to be materially different from current expectations.

Exclusion of Liability: To the fullest extent allowed by law, Edison shall not be liable for any direct, indirect or consequential losses, loss of profits, damages, costs or expenses incurred or suffered by you arising out or in connection with the access to, use of or reliance on any information contained on this note.

No personalised advice: The information that we provide should not be construed in any manner whatsoever as, personalised advice. Also, the information provided by us should not be construed by any subscriber or prospective subscriber as Edison’s solicitation to effect, or attempt to effect, any transaction in a security. The securities described in the report may not be eligible for sale in all jurisdictions or to certain categories of investors.

Investment in securities mentioned: Edison has a restrictive policy relating to personal dealing and conflicts of interest. Edison Group does not conduct any investment business and, accordingly, does not itself hold any positions in the securities mentioned in this report. However, the respective directors, officers, employees and contractors of Edison may have a position in any or related securities mentioned in this report, subject to Edison's policies on personal dealing and conflicts of interest.

Copyright: Copyright 2021 Edison Investment Research Limited (Edison).

Australia

Edison Investment Research Pty Ltd (Edison AU) is the Australian subsidiary of Edison. Edison AU is a Corporate Authorised Representative (1252501) of Crown Wealth Group Pty Ltd who holds an Australian Financial Services Licence (Number: 494274). This research is issued in Australia by Edison AU and any access to it, is intended only for "wholesale clients" within the meaning of the Corporations Act 2001 of Australia. Any advice given by Edison AU is general advice only and does not take into account your personal circumstances, needs or objectives. You should, before acting on this advice, consider the appropriateness of the advice, having regard to your objectives, financial situation and needs. If our advice relates to the acquisition, or possible acquisition, of a particular financial product you should read any relevant Product Disclosure Statement or like instrument.

New Zealand

The research in this document is intended for New Zealand resident professional financial advisers or brokers (for use in their roles as financial advisers or brokers) and habitual investors who are “wholesale clients” for the purpose of the Financial Advisers Act 2008 (FAA) (as described in sections 5(c) (1)(a), (b) and (c) of the FAA). This is not a solicitation or inducement to buy, sell, subscribe, or underwrite any securities mentioned or in the topic of this document. For the purpose of the FAA, the content of this report is of a general nature, is intended as a source of general information only and is not intended to constitute a recommendation or opinion in relation to acquiring or disposing (including refraining from acquiring or disposing) of securities. The distribution of this document is not a “personalised service” and, to the extent that it contains any financial advice, is intended only as a “class service” provided by Edison within the meaning of the FAA (i.e. without taking into account the particular financial situation or goals of any person). As such, it should not be relied upon in making an investment decision.

United Kingdom

This document is prepared and provided by Edison for information purposes only and should not be construed as an offer or solicitation for investment in any securities mentioned or in the topic of this document. A marketing communication under FCA Rules, this document has not been prepared in accordance with the legal requirements designed to promote the independence of investment research and is not subject to any prohibition on dealing ahead of the dissemination of investment research.

This Communication is being distributed in the United Kingdom and is directed only at (i) persons having professional experience in matters relating to investments, i.e. investment professionals within the meaning of Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005, as amended (the "FPO") (ii) high net-worth companies, unincorporated associations or other bodies within the meaning of Article 49 of the FPO and (iii) persons to whom it is otherwise lawful to distribute it. The investment or investment activity to which this document relates is available only to such persons. It is not intended that this document be distributed or passed on, directly or indirectly, to any other class of persons and in any event and under no circumstances should persons of any other description rely on or act upon the contents of this document.

This Communication is being supplied to you solely for your information and may not be reproduced by, further distributed to or published in whole or in part by, any other person.

United States

Edison relies upon the "publishers' exclusion" from the definition of investment adviser under Section 202(a)(11) of the Investment Advisers Act of 1940 and corresponding state securities laws. This report is a bona fide publication of general and regular circulation offering impersonal investment-related advice, not tailored to a specific investment portfolio or the needs of current and/or prospective subscribers. As such, Edison does not offer or provide personal advice and the research provided is for informational purposes only. No mention of a particular security in this report constitutes a recommendation to buy, sell or hold that or any security, or that any particular security, portfolio of securities, transaction or investment strategy is suitable for any specific person.

Frankfurt +49 (0)69 78 8076 960

Schumannstrasse 34b

60325 Frankfurt

Germany

London +44 (0)20 3077 5700

280 High Holborn

London, WC1V 7EE

United Kingdom

New York +1 646 653 7026

1185 Avenue of the Americas

3rd Floor, New York, NY 10036

United States of America

Sydney +61 (0)2 8249 8342

Level 4, Office 1205

95 Pitt Street, Sydney

NSW 2000, Australia

Frankfurt +49 (0)69 78 8076 960

Schumannstrasse 34b

60325 Frankfurt

Germany

London +44 (0)20 3077 5700

280 High Holborn

London, WC1V 7EE

United Kingdom

New York +1 646 653 7026

1185 Avenue of the Americas

3rd Floor, New York, NY 10036

United States of America

Sydney +61 (0)2 8249 8342

Level 4, Office 1205

95 Pitt Street, Sydney

NSW 2000, Australia

More on Patria Private Equity Trust

View All

Latest from the Investment Companies sector

View All Investment Companies content

Research: Healthcare

Nicox — Mississippi data shows benefit in dry eye

While the Phase IIb Mississippi study in patients with acute exacerbations of blepharitis did not meet the primary endpoints in that indication, a post-hoc analysis showed potentially promising data that NCX-4251 could provide clinical benefit in patients with dry eye disease (DED), a c $5bn market. Given that blepharitis is commonly associated with DED, of the 224 enrolled patients, 123 were found to have inferior corneal staining (by a score of at least two on a five-point scale), a key sign of DED. Among these 123 patients, there was a statistically significant difference versus placebo in the change from baseline in eye dryness scores (assessed on a validated Visual Analog Scale). Significant differences were also observed in other DED symptoms (including photophobia, blurred vision, burning/stinging, pain and others) at all measured time points in the 14-day treatment, and for some, the effects persisted for up to two weeks after the end of treatment. The company plans to meet the FDA in early 2022 to discuss a potential alternate development path for NCX-4251.

Continue Reading

Subscribe to Edison

Get access to the very latest content matched to your personal investment style.

Sign up for free